Introduction: Thyroid disease is the worlds second most frequent endocrine condition after diabetes. Nearly 300 million individuals worldwide are affected. Moreover, approximately 60% of people with thyroid disease are completely unaware of their medical condition. Thyroid disease might have been an underlying disease leading to death, even if its not the primary cause of death. Methods: This type of research is descriptive research with a retrospective study design using secondary data from medical records of patients with thyroid disease at the Endocrine Clinic, Dr. Soetomo General Academic Hospital from January 2019 - December 2020. Results: Among 897 cases, thyroid disease was found to be more prevalent in females (79.2%). It was also discovered that most sufferers (22.4%) were between 50 and 59 years old. In hyperthyroidism, the highest prevalence was found in thyrotoxicosis, unspecified (ICD E05.9) (75.3%). The most common type of hypothyroidism was found in hypothyroidism, unspecified (ICD E03.9) (90.8%). The most common euthyroidism was malignant neoplasm of thyroid gland (ICD C73) (52.3%). It also showed in thyroiditis that the highest prevalence was found in thyroiditis, unspecified (E06.9) (75%). Conclusion: The prevalence of thyroid disorders is more significant in females and the 50-59 age group. Thyrotoxicosis, unspecified (ICD E05.9), hypothyroidism, unspecified (ICD E03.9), Malignant neoplasm of thyroid gland (ICD C73), and Thyroiditis, unspecified (ICD E06.9) were the most common thyroid diseases.

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