Medicine, Health & Food

Medicine, Health & Food

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Effects of High-Intensity Interval Exercise on Interleukin 6 Levels in Healthy Male Adolescents

Volume: 136  ,  Issue: 1 , November    Published Date: 06 November 2023
Publisher Name: IJRP
Views: 204  ,  Download: 122 , Pages: 56 - 62    
DOI: 10.47119/IJRP10013611120235613


# Author Name
1 Olivia Andiana
2 Mahmud Yunus
3 Slamet Raharjo
4 Ulul Azmi Annur Putra
5 Raja Mohammed Firhad Raja Azidin


This study aims to prove the effects of high-intensity interval exercise on interleukin 6 (IL-6) levels in healthy male adolescents. Twenty healthy male adolescents aged twenty to twenty-five years with a body mass index (BMI) of 19-24 kg/m2 were given one session of high-intensity interval exercise intervention by pedaling an ergocycle for 40 minutes. The ELISA method evaluated IL-6 levels between pretest and posttest in both groups. The data analysis technique uses a Paired Sample T-Test with a significance level of 5%. The results showed that there was an increase in the average IL-6 levels between the pretest and posttest in the high-intensity interval exercise group (p ≤ 0.05). In contrast, in the control group there was no significant difference in the average IL-6 levels. 6 between pretest and posttest (p ≥ 0.05). It is proven that one session of high-intensity interval exercise increases IL-6 levels in healthy male adolescents.


  • High-intensity interval exercise
  • ergocycle exercise
  • IL-6 levels
  • metabolism