As a leading city in the Chinese economy, Beijing has gradually transformed its industrial structure to centralized, large-scale, and high-end industries. In recent years, the migrant labor force and permanent population in Beijing have increased year by year, and the population pressure has further expanded. With the adjustment of the industrial structure, the demand for labor has changed, and the labor force has moved on a large scale. This article takes Beijing as the research object and adopts a combination of qualitative and quantitative research methods to further explore the changes in Beijing?s industrial structure from the perspective of labor mobility. First, by analyzing the correlation between labor mobility and industrial structure changes in Beijing, the measurement indicators of its migrant labor are determined. Secondly, by defining the measurement of industrial structure adjustment, using relevant data from the Beijing Statistical Yearbook, and analyzing the correlation between labor mobility and industrial structure changes through the analysis method of gray correlation. Finally, regarding the problems in Beijing?s industrial adjustment under the background of labor mobility, it is proposed to improve the disadvantages of Beijing?s industrial structure adjustment through three aspects: increasing government support, improving labor market information, and avoiding employment competition pressure, in order to provide reference for Beijing.