This study aimed to determine the relationship between recurrent abdominal pain and Helicobacter pylori infection in children. The cross sectional study was conducted 56 children. Subjects were children between aged 2-18 years with complaints of abdominal pain based on the Rome IV criteria according to the inclusion and exclusion criteria. Interview was carried out to establish the diagnosis of recurrent abdominal pain. Helicobacter pylori infection was determined based on Helicobacter Pylori Stool Antigen (HPSA) test measurements.From 56 samples, there were 36 children with positive HPSA and 20 children with negative HPSA. Symptoms of abdominal pain occurred in 16 children (44.4%) in the HPSA positive group, while in the HPSA negative group all had abdominal pain. There was a significant association between abdominal pain symptoms and H. pylori infection (p <0.001).