Comparison of the Accuracy of Helicobacter pylori Stool Antigen (HPSA) Test with Campylobacter Like Organism (CLO) Test in Diagnostic of Helicobacter Pylori Gastritis in Children
Open Access
Journal Type:Methodology Article
Subject Field:Gastroenterology
Downloads:931
Publish Date:November 21, 2020 7:00 pm
Views:1091
Volume:64, Issue: 1, November, 2020
Subject:Medicine, Health & Food
Pages:89-95
Abstract
This study aimed to find the accuracy of the HPSA test with the CLO test in diagnosing helicobacter pylori gastritis in
children. The cross sectional study conducted on 57 children with gastritis in October 2019 up to May 2020. Subject were
children between two until eighteen years old who met the inclusion and exclusion criteria. HPSA examination was
performed on the patient's stool sample using rapid immunochromatographic monoclonal antibody test for qualitative
detection of H. pylori bacteria in human feces. From 57 samples, there were 37 children positively infected H. pillory.
There were no difference in characteristics in the study population. The diagnostic value of the HPSA test showed a
sensitivity and specificity of 83.8% and 95%. The positive and negative predictive value are 96.9% and 76% (PPV and
NPV) with positive and negative likelihood ratio (LR + and LR -) are 16.76% and 0.17%, and an accuracy value of
87.7%.