Abstract Background: Hypertrophic cardiomyopathy (HCM) is a clinically and morphologically heterogeneous genetic inherited cardiovascular disease that is often associated with unfavourable prognosis and leading to early death. Case description: A young man suffering from chest pain with family history of sudden cardiac death . Electrocardiography showed left ventricular hypertrophy. Echocardiography demonstrated left ventricle concentric remodelling . However, exercise stress test and computed tomography-scan were unremarkable. Cardiovascular magnetic resonance imaging (CMR I ) Eventually revealed the presence of l ate phase patchy myocardial enhancement at anteroseptal, septal, infero-septal in mid left ventricle , super io r and inferior left-right ventricle, asymmetrical insertion point of the left ventricle septum indicating HCM. Conclusion: HCM is often found on young adults and mostly affected by genetic factor. Clinical examination and family history can assist the diagnosis of HCM. Echocardiography investigations can help direct HCM. CMRI is a more sensitive and less invasive diagnostic modality. Treatment includes beta blockers, septal myomectomy , and alcohol septal ablation. The latter is done frequently in Indonesia despite the high recurrence rate. Physical activity with light and moderate exercise can improve functional status and life quality in HCM patients.