In Western World, the prevalence of breast cancer has become a public health issue and increasing with high mortality rate. Currently,such increasing trend has been recorded in Australia with approximately 1.38 million female population diagnosed of breast cancer. Advances in cancer screening, detection and treatment have improved the survival rate of those diagnosed with breast cancer. Studies conducted using randomised control trial, Cohort studies and Case- control studies have identified life style factors, medical and socio-economic factors as risk factors predisposing individual to the risk of developing breast cancer. In this systematic review, high quality assessment was graded on some of the studies. There were strong evidence with high consistent finding on the association between the physical inactivity, post-menopausal obesity and alcoholic consumption on the risk of developing breast cancer. There was moderate evidence on the association of hormonal contraceptive and family history in causing breast cancer; and limited evidence on the association of body mass obesity, fat consumption and age in breast cancer formation. To reduce the risk factors affecting the prevalence of breast cancer among the targeted age group in Australia, gymnastic facilities for physical activities should be provided to the population. Life style factors such as adequate dietary intake, cessation of cigarette smoking and reduction in pre-and post- menopausal exposures to hormones should be promoted among the population residing in rural and urban regions. The use of X-ray mammography, chemo preventive, prophylactic surgery or prophylactic prevention mastectomy should be encouraged. Financial and emotional support should be provided to those residing in rural areas that are unmarried and jobless, and finds it difficult to cope with living conditions.