This is a constructive summary of the evolution of COVID 19 to the human population. In this review, the researchers tried to summarized the research conducted on the evolution of the coronavirus. The purpose of this review is to aggregate and summarized all researches conducted to examine the evolution of the Coronavirus in the human population utilizing the integrative review process. Integrative review research design was used and included articles from 2020 to 2021. Search terms such as ??Evolution of coronavirus?? and ???? were used to identify scientific publications. Of 281 studies identified, 5 articles were included and rated using the Canadian Medical Association and Center for Evidence-Based Medicine Level of Evidence ranking system. The Coronavirus contained viral sub genomic messenger RNAs (sgmRNAs) which replicates in the respiratory tract. Cluster infections play a major role in the increase incidence of COVID 19. The infections were affected by factors that include containment measures and screening process. COVID 19. Clinical manifestations of COVID 19 mimic the respiratory problems in the neopediatric population