Background: Lung cancer is the most common cause of death in the world, mostly in high-income countries, at Friendship Hospital, adenocarcinoma is the most common type. Simple and rapid diagnosis is very important in reducing morbidity and mortality. One of the examination techniques used is a core biopsy. This study aims to determine the profile of lung adenocarcinoma patients using the core biopsy method at the HAM Hospital in 2017-2019. Methods: This study is descriptive with a cross sectional approach, with samples of all patients diagnosed with lung adenocarcinoma histopathologically through core biopsy, the number of samples is 108 samples with total sampling method. Results and discussion: the mean age is 57 ? SD 11.71 years, the youngest is 18 years old and the oldest is 74 years old. 34 men (85%), Batak 17 people (42.5%) and Acehnese 1 person (2.5%), farmer work 20 people (50%) and civil servant job 4 people (10%), smoking history 32 people (80%), the most location in the peripheral area 24 cases (60%), diameter 2 cm 12 people (30%) and > 2 - 3 cm 6 people (12%), stage IVA 21 people ( 52.5%) and IIIA in 1 person (2.5%), solid variant adenocarcinoma 21 people (52.5%) and enteric adenocarcinoma in 1 person (2.5%). Conclusion: In this study, the oldest age was 74 years, male gender, Batak ethnicity, farmer occupation, smoking history, location in peripheral areas, diameter 2 cm, stage IVA, solid adenocarcinoma was the most variant.