Journal Details
Clinical Characteristics and Survival in Non-Epithelial Ovarian Cancer
Open AccessJournal Type: Review ArticleSubject: Medicine, Health & FoodSubject Field: Gynecology and ObstetricsVolume:92, Issue: 1, January, 2022Publish Date: 13 January 2022
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Views: 664
Pages: 547-562
Abstract
Ovarian cancer is often asymptomatic, grows rapidly and most diagnosed at advanced stage. Till now there is no method for early detection. Its incidence and mortality rate are increasing. Actually, non-epithelial type of ovarian cancer most found in young women and has better prognosis with adequate therapy. The main therapy for non-epithelial ovarian cancer is surgery, both radical and conservative (fertility sparing). Postoperative chemotherapy depends on the type and stage, although platinum-based chemotherapy regimens are used in almost all cases because of their chemosensitivity. The first-line regimens used are bleomycin, etoposide and cisplatin. Some clinical characteristics could affect prognosis including recurrence and survival rate. They include patient?s age, cancer stage, tumor size, tumor marker, post-operative tumor residue, histopathological type of cancer, and chemotherapy. Better knowledge of those prognostic factor will lead to better management of patients with non-epithelial ovarian cancer and increase survival rate.