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Clinical Characteristics and Survival in Non-Epithelial Ovarian Cancer

Open Access

Journal Type:Review Article

Subject:Medicine, Health & Food

Subject Field:Gynecology and Obstetrics

Volume:92, Issue: 1, January, 2022

Publish Date:12 January 2022 7:00 pm

Pages:547-562

Download:615

Views:664

Abstract

Ovarian cancer is often asymptomatic, grows rapidly and most diagnosed at advanced stage. Till now there is no method for early detection. Its incidence and mortality rate are increasing. Actually, non-epithelial type of ovarian cancer most found in young women and has better prognosis with adequate therapy. The main therapy for non-epithelial ovarian cancer is surgery, both radical and conservative (fertility sparing). Postoperative chemotherapy depends on the type and stage, although platinum-based chemotherapy regimens are used in almost all cases because of their chemosensitivity. The first-line regimens used are bleomycin, etoposide and cisplatin. Some clinical characteristics could affect prognosis including recurrence and survival rate. They include patient?s age, cancer stage, tumor size, tumor marker, post-operative tumor residue, histopathological type of cancer, and chemotherapy. Better knowledge of those prognostic factor will lead to better management of patients with non-epithelial ovarian cancer and increase survival rate.

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