Pre-marital sex is a sexual activity with the opposite or same sex before marriage. In Indonesia, an Information Center and Youth Counseling or Pusat Informasi dan Konseling Remaja (PIK-R) was established to improve attitude and pre-marital sex behavior among adolescents. This study aims to examine the relationship between the utilization of PIK-R towards the attitude and practice of pre-marital sex. This is a cross-sectional study. The sampling technique used was simple random sampling. Data were collected with an online questionnaire. The sample size of the study was 144 respondents. Data were analyzed with univariate analyses, bivariate analyses with chi-square statistical test, and multivariate analysis with multiple logistic regressions. Bivariate analyses found that, the usage of PIK-R has a significant relationship to attitude (p=.015) and pre-marital sex practices (p=.037). In multiple binary logistic regression, controlling for age, sex, media access and peers, the use of PIK-R has a relationship to attitude (AOR=1.871, 95% CI=1.202-2.912 p=.006) and pre-marital sex (AOR=.564, 95% CI=.362-.877, p=.011). In conclusion, the use of PIK-R service affected one?s attitude toward pre-marital sex and decreased its practices. More study qualitative research is needed to determine the effectiveness of PIK-R and other factors that affect attitude and practices of pre-marital sex