Fine needle aspiration cytology is a rapid diagnostic technique and has advantages over traditional incisional biopsy. Fine needle aspiration cytology of soft tissue lesions, if supported by clinical and diagnostic data, will provide accurate results. Fine needle aspiration cytology has the advantage of significantly reducing discomfort, has a very low risk of complications, and can be performed from multiple sides, thus providing a more representative material. The aim of this study was to provide clinicopathological profile of fine needle aspiration cytology of soft tissue tumor in Anatomical Pathology Department of Dr. Soetomo General Academic Hospital during 2014 - 2018. This study used a descriptive observasional research with retrospective approach. The samples are all patient with soft tissue tumor which had fine needle aspiration cytology examination and with/without confirmation of histopathological examination at the Anatomical Pathology Department of Dr. Soetomo General Academic Hospital during 1 January 2014 - 31 December 2018. The data was obtained for five years, there were 244 cases of fine needle aspiration of soft tissue tumors, the most gender was female consist of 128 cases (52.46%). There were more benign cases (155 cases (63.52%)) than malignant cases, and there were discrepancies in the results with histopathology in 9 cases (9.18%) and with immunohistochemical examination in 5 cases (5.10%).