Epidemology studies aim at investigation of diseases prevalence on biophysical and sociocultural milleux considerations available literature reveal that there is death or near absence of information on ecological consideration in etiology of diseases in the area under consideration. This study therefore directs attention to investigation of the spatial and temporal prevalence of certain diseases in theory ecological domains. The diseases were investigated in their ecological riches. Two hypothesis were formulated and the data collected were presented tables for statistical analsysis. Two techniques were used in the analysis of data which have the one way analysis of variance(ANOVA) and the chi-square statistics. The results showed that there is a significant relationship in the spatial incidence of disease while there is no significance variation in the seasonal incidence.