Background: PTB is the common case found in many endemic countries. The misdiagnosis of PTB is often happening because it mimics malignancy and is difficult to distinguish from another infection. Cases Presentation: Here presented three PTB cases, a male 23 years old, and two female patients 16 and 32 years old, respectively. The patients were initially suspected of intra-abdominal malignancy and finally confirmed as PTB after CT Scan and pathological examination. After several months of OAT treatment, the patient improved then the complaints are decreased. Conclusion: PTB is a disease that closely resembles a malignancy such as peritoneal carcinomatosis, and is difficult to distinguish from another infection. An adequate understanding of PTB characteristics on CT scans will be very helpful in establishing the diagnosis of these cases