Background: Fluid management is a critical component for the management of critically ill children. This condition requires an examination to assess intravascular volume. Assessment of central venous pressure (CVP) is often used in critically ill children. Still, it is an invasive procedure that is prone to various complications, while measurement of the inferior vena cava distensibility index (IVC-DI) with ultrasound is a non-invasive procedure that can also be used to assess volume status in critically ill children. Objective: To determine the correlation between central venous pressure and inferior vena cava distensibility index to assess volume status in critically ill children. Methods: Analytic cross-sectional study was carried out in PICU RSUP H. Adam Malik Medan from December 2021 until January 2022. Samples were patients aged from 1 month to 18 years hospitalized in PICU with a central vein catheter installed and mechanical ventilation. Exclusion criteria were defined as patients with heart failure, hemothorax, pneumothorax, and hemopneumothorax. This study was conducted by examining central venous pressure (CVP). Then, the USG doppler was used simultaneously to assess the inferior vena cava distensibility index (IVC-DI). The correlation between central venous pressure and inferior vena cava distensibility index was assessed using the Spearman Correlation test or Kruskal Wallis test. Results: CVP and IVC-DI values had a strong correlation in negative correlation and the result was statistically significant (r=-0,623, p= 0,003). Meanwhile, a significant correlation positive was found between CVP and volume status (r= 0,940, p= <0,001) but it had negative correlation with IVC-DI (r= -0,573, p=0,008). Conclusion: There was a negative correlation between central venous pressure and inferior vena cava distensibility index for assessing volume status in critically ill children.