Acute Respiratory Infection (ARI) is a disease that infects the upper respiratory tract and lower respiratory tract. One of the risk factors for ARI disease is the physical sanitation of the house. The physical sanitation components of the house are the ventilation of the house, the ownership of the smoke hole, the density of the room occupancy, the type of floor and the type of wall. The purpose of this study was to determine the relationship between physical sanitation of the house and the incidence of ARI among children under five in the working area of ??the Naioni Health Center. The type of research used is analytic with a cross sectional research design. The population in this study were all children under five who were in the working area of ??the Naioni Health Center which amounted to 1,142 toddlers.The Collection data used interview, observation and measurement techniques for 92 toddlers using proportional random sampling technique. Bivariate analysis using Chi-Square statistical test. The results showed that the variables related to the incidence of ARI were house ventilation (p value = 0.000?0,05), smoke hole ownership (p value = 0.000?0,05), room occupancy density (p value = 0.003?0,05), type of floor (p value = 0.004?0,05) and the type of wall (p value = 0.019?0,05). The Naioni Health Center is expecting to continue to make prevention efforts and counseling about healthy homes to the entire community.