Motivation and motives play the most critical role in human actions. The power of authority and intellect is the main difference between humans and other creatures, shaping intention and motive in him, leading to action, and ultimately bringing about fortune or misfortune. Nahj al-Fe???a, which provides narrations and words of Muhammad (PBUH) in ethics and virtues, comprises many hadiths about the significance of intention or motive, establishing the impression in the reader that motive is much more important than the action. Since Islam is the religion of human life and should include all its dimensions, it is worth examining the effect of motivation on human prosperity from the perspective of religion. This article first defines motives and motivation from a psychological perspective while examining the importance of intention and motivation in people's behaviors. Then, the internal and external motives and their importance are discussed, with a focus on the role of each in daily human activities (such as making a living, gaining knowledge, marriage, etc.) to achieve eternal prosperity from the perspective of Islam.