This study is focused on assessing the air quality status of particulate matter pollution in two industrial nuclei (Niger Mills Flour Industry and UNICEM/LAFARGE cement industries) in Calabar Cross River State, Nigeria. The imperative for the study derives from the recognition that particulate matter(PM ) as one of the six criteria pollutants has a significant human and ecological implication in our environment. Pm has been implicated for many deleterious effects on human health. The study objectives include: (i)determination of the volumetric concentration of particulate matter in the ambient air, (ii) understanding of the nature of particulate constituents, (iii) isolation of particulate constituents from other pollutants and , (iv) ascertaining the permissible levels of pollutants and comparison of the air quality status of the two areas. The literature explored such thematic areas as human and environmental impact of particulate pollutants, and air quality standards and indices. The methodology involved the employment of specialized instruments in sampling and recording the air quality status in selected stations mapped out by the Global positioning system GPS) in the two industrial sites. The field air sampling were conducted in two seasons dry seas in (Feb 2018) and wet season (May. 2018) the obtained results were presented in tables(Tables 1-4). These table were further summarized and compared with the Federal Ministry of Environment (FME) air quality criteria (Table5-8). The findings reveal that the ambient air quality of two location were not exceedingly above the Federal Ministry of Environment (FME) permissible limits. Secondly, that air quality status at Flour Mills is higher than that of the UNICEM/LAFARG cement industry are. Thirdly, that the air quality status at large is more homogenous than that of the flour mills area at Calabar central area. Finally that health implication of air quality assessment of the two areas is not threatened in the short run.