As the development of the aviation industry, airports often work continuously with operations 24 hours a day, seven days a week, causing many requests for passengers to travel. With the large number of requests, the more frequent interactions between employees and passengers, but not all interactions can run well, a lot of bad events happened on the airlines. The purpose of this study was to determine whether there was an influence between cultural intelligence, emotional regulation on burnout at airline X employees. The participants in this study were 62 airline X employees. The data analysis technique used in this study was multiple linear regression. The results showed that cultural intelligence and emotional regulation had no effect on burnout at airline X employees.