Introduction This study aims to evaluate the clinical outcome of the Single Rod Operation (SRD) surgical technique in AIS at Haji Adam Malik General Hospital Medan. Methods A retrospective cross-sectional study was conducted in 2016-2020 at Haji Adam Malik General Hospital Medan. The subjects in this study were Adolescent Idiopathic Scoliosis (AIS) patients who had undergone surgery with the SRD technique and had complete medical record data including demographic data, onset, kyphosis angle before and after surgery, and Cobb angle before and after surgery. Results This study involved 23 female AIS subjects with a mean age of 16.09 years. The most common Lenke-based diagnoses were AIS Lenke 1 (52.2%), followed by AIS Lenke 3 (26.1%), AIS Lenke 6 (13%), and AIS Lenke 4 and 5 (4.3%). In this study, there were no patients with AIS Lenke 2. The average change in the angle of kyphosis before and after surgery showed significant results (25.830 VS 15.910 p<0.001) with a mean correction of 31.82%. There was a significant difference in the mean Cobb angle before and after SRD surgery (67.260 vs 34.870, p<0.001). SRD is able to correct the Cobb angle with an average of 48.69%. The mean blood volume during SRD surgery was 393.48 ml with an average surgical duration for 249.13 minutes. Conclusion The SRD technique significantly improves the kyphosis and Cobb angles so that it can be a good surgical option for patients with AIS.