Introduction: This case report aims to describe an emergency condition of myasthenia gravis in a young adult with a myasthenic crisis due to infected bronchiectasis. The highlight of this case report was the risk factor and the best management of this patient myasthenic crisis episode. Case Description: A 28-years-old male with early-onset generalized myasthenia gravis came with an emergency condition as a myasthenic crisis in the first month of his therapy. This myasthenic crisis condition was concomitant with infected bronchiectasis, which was predicted as the underlying cause. A myasthenic crisis caused by infected bronchiectasis is a rare case that requires extensive airway support and antibiotics.  Conclusion: Myasthenic crisis concomitant with bronchiectasis is a rare condition. Both of these conditions could lead to mortality. Extensive and aggressive treatment and guidelines are needed to manage this case. Since bronchiectasis is a permanent condition that tends to occur again in the future, proactive management has to be done to prevent infection and recurrent dyspnea.