Abstract. Most patients who have been diagnosed with cancer are filled with anxiety and fear of facing the threat of death and pain while undergoing therapy. Many previous studies discussed social support for hope. So is research that discusses social support for resilience. Interestingly there are no studies that specifically discuss expectations, social support for resilience. This study examines the role of hope and social support, towards resilience in cancer patients. This study uses quantitative methods. The response of this study consisted of 52 respondents consisting of 14 men and 38 women. Based on the results of the study, concluded that there was a significant effect of expectations and social support on resilience in cancer patients.