A new transformation of industry known as Industry 4.0 has drawn much attention among researchers and entrepreneurs. From a higher education perspective, Industry 4.0 has grown concerned about how institutions can produce graduates that are compatible with Industry 4.0. Due to the high business operation migrated to the online platforms, there is a need for graduates that have Information Technology (IT) skills, thinking skills, critical skills, and communication skills. A lack of necessary skills and knowledge of the Fourth Industrial Revolution (4IR) will lead to high unemployment among graduates. This paper aims to assess the relationship between Education 4.0 and Industry 4.0. Also, how e-learning plays a role while promoting lifelong learning. Thus, this leads to the development of the Education-Industry 4.0 Framework. A descriptive literature review on Education 4.0 and Industry 4.0 intends to identify and improve the millennial skills and knowledge. The descriptive literature identified four elements of Education 4.0, six crucial skills of millennial graduates, and seven technologies of Industry 4.0. The interrelationship between Education 4.0, millennial graduates, and Industry 4.0 was identified. Furthermore, this paper identified e-learning as a component of closing the gap between Education 4.0 and Industry 4.0. Even though there has been a lot of research on Education 4.0 and Industry 4.0, this paper aims to provide descriptive literature that provides a guideline on how Education 4.0 can produce graduates that meet the industry 4.0 requirements through e-learning to promote sustainable education.