Myopia as an abnormal eye condition that gives blurry vision due to the image lies in front of the retina. It becomes an epidemic case in the world as the prevalence keeps increasing over time. Experimental studies using animals are useful to understand the establishment of myopia so that it can be used for further study in preventing myopia. Form deprivation myopia (FDM) is one of the most common methods to make a myopic condition in the eye of the animal model with many parameters to measure, hence the purpose of this article is to review the form deprivation myopia effect in the sclera layer of the animal models eye.