The purpose of this study is to provide a comprehensive systematic literature review of digital learning strategies within universities (institutions of higher learning) in developing countries. Further, the paper seeks to identify gaps for further research, as well as point out future research agenda for digital learning strategies within universities in developing countries. A structured literature review method was used in this study. Journal articles published between year 2011 and 2021 were reviewed to inform this study. A total of 16 articles were identified and reviewed. From the findings, strategies for digital learning are not to be ignored for optimal delivery of digital learning both for the student and for the instructor. Future research should leverage big data produced from the use of the learning platforms and investigate how the incorporation of advanced learning technologies could advance institutional value.