In this study, the combination of biosynthesized silver nanoparticles and clindamycin, a ribosomal antibiotic, was investigated by Kirby Bauer Disk Diffusion Assay. First, an aqueous extract of Hagnaya Fern was prepared to synthesize SNP from a silver nitrate solution. The nano-Ags were then subjected to UV-Vis spectroscopy. By the maximum absorbance at 400 nm, it was concluded that the biosynthesized SNPs are spherical in nature. The mean inhibition halo for biosynthesized SNP, clindamycin, and CSNP was 9.75 mm, 31.75 mm, and 36 mm, respectively. The results showed that silver nanoparticles derived using Stenochlaena palustris leaf extract are an effective adjuvant for clindamycin against MRSA and can be used for its synergism with the antibiotic.