The study aimed to determine the level of and establish a significant relationship between students interpersonal relationships and good manners practices in school. The study was conducted at Rosario National High School (RNHS) and Balagnan Integrated School (BIS) in Balingasag Central District, Division of Misamis Oriental, during the school year 2022-2023 with two-hundred twenty-one respondents (221). The study utilized the descriptive-correlational research design and used a questionnaire as the main instrument to gather relevant information.  Mean and Standard Deviation were used to determine the level of interpersonal relationships and good manners practices among students in school. Pearson r correlation was employed to establish the significant relationship between interpersonal relationships and good manners practices among students in school. Results revealed that students at RNHS and BIS have very high level of interpersonal relationships, a very high level of good manners practices as to respect, politeness, and civility, and a high level of good manners practices as to graciousness. They also have significant relationships between interpersonal relationships and good manners practices in school. It is recommended that parents and teachers collaborate with one another to constantly communicate and interact with students because they are the models of these values. It is suggested that parents always remind their children of the importance of these values to their character formation.