The current study aimed to determine lexical effects on spoken word recognition in Persian-speaking preschool-aged children with normal hearing. The research, as a cross-sectional study, was administered in sixty-two 4-to-6-year-old children who were recruited using convenient sampling from a preschool center in Shiraz city, Iran. The preschool version of the Persian Lexical Neighborhood Tests (PLNTs-PV) was used, including four subscales. It has been demonstrated that word lexical difficulty and word length affected the Persian-speaking 4-to-6-year-old childrens speech-in-noise performance. The PLNTs-PV can be used measuring speech-in-noise recognition in Persian-speaking preschool-aged children. We recommend managing the environments noise as one of the practical solutions to improve preschool-aged childrens speech recognition performance.