Background: Autoimmune rheumatic diseases (ARDs) are a group of rheumatic diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis which most infect connective tissue and cause organ damage. Autoimmune rheumatic diseases (ARDs) can manifest in many organs of the body such as the lungs, heart, kidneys, skin, and eyes. Several studies show that ARDs can cause a manifestation in the eye and can be severe. This literature study aims to describe the definition of systemic lupus erythematosus, its etiology, epidemiology, and ophthalmic manifestations. Objective: This literature study aims to describe and show the ophthalmic manifestations of ARDs. Method: This study uses a literature review as the method. Results: Several studies found and will be reviewed in this research about ophthalmic manifestations in patients with ARDs. Conclusions: Keratoconjunctivitis sicca or dry eye syndrome was found as the most common ophthalmic manifestation in patients with ARDs.