Post COVID-19 Syndrome or PCS is a group of prolonged symptoms that are experienced by COVID-19 patients and remained at least two months after the infection were healed. This condition could lower the quality of life of the patient after the infection of COVID-19. Some treatment approach has been introduced to treat PCS including conventional therapies, and non-conventional therapies such as rehabilitation were suggested to treat PCS. This narrative review will explain what is PCS, the pathophysiology of PCS, and how rehabilitation works to treat Post COVID-19 Syndrome. A literature search using online databases PubMed, and ScienceDirect using keyword: “Post COVID-19”, AND “rehabilitation”, OR “physical rehabilitation”, OR “psychological rehabilitation”, OR “neuropsychology rehabilitation”, OR “medical device-based rehabilitation” OR “infectious disease”, AND “efficacy” to find all studies that are relevant. The type of studies that covered in this review are experimental studies, clinical trials, and in-silico studies. Our review finds that rehabilitation have a promising potential in treating PCS. Therefore, more research on additional forms of therapy that were left out of this review but may be useful in addressing Post COVID-19 Syndrome.