main objective was the training of the nursing team regarding the application of the plan of care the patient in home hospitalization in the city of São Paulo, in the home program at the Municipal hospital in the city of São Paulo, in the home program called Better at home wich will be applied the daily therapeutic plan for the application of injectable antibiotics. An intervention project was developed, where a unique therapeutic plan was developed for patients with antibiotic therapy, with this is desired to reduce the demandas for hospital, aiming at reducing costs for the instituiton, a humanized care centered on care with proposal of home care that includes reorganization of work processes by the health team and discussion about different conceptions and approaches to the family.