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EFFECTIVENESS OF INTRA-ARTICULAR INJECTION OF HIALURONIC ACID ON ARTHOGENIC CONTRACTURES OF RAT KNEE JOINTS IN THE REMOBILIZATION PHASE

Volume: 148  ,  Issue: 1 , May    Published Date: 04 May 2024
Publisher Name: IJRP
Views: 47  ,  Download: 33 , Pages: 202 - 209    
DOI: 10.47119/IJRP1001481520246392

Authors

# Author Name
1 Steven Tigor Maruhum Hutabarat
2 Otman Siregar
3 Andriandi

Abstract

Introduction: The study examines the impact of intra-articular hyaluronic acid injections on arthrogenic contractures in rat knee joints, focusing on the remobilization phase after immobilization-induced contractures. Methods: Utilizing a controlled experimental design, the study involved rats with induced knee joint immobilization, followed by treatment with intra-articular injections of hyaluronic acid. Measurements of range of motion (ROM) were used to assess the effectiveness of the treatment. Results: The treatment group showed a significant improvement in knee joint ROM compared to controls, indicating that hyaluronic acid injections effectively reduce contractures and improve mobility. Discussion: The findings support the therapeutic potential of hyaluronic acid in treating joint contractures, suggesting a beneficial approach for post-immobilization recovery in clinical settings. Introduction: The study examines the impact of intra-articular hyaluronic acid injections on arthrogenic contractures in rat knee joints, focusing on the remobilization phase after immobilization-induced contractures. Methods: Utilizing a controlled experimental design, the study involved rats with induced knee joint immobilization, followed by treatment with intra-articular injections of hyaluronic acid. Measurements of range of motion (ROM) were used to assess the effectiveness of the treatment. Results: The treatment group showed a significant improvement in knee joint ROM compared to controls, indicating that hyaluronic acid injections effectively reduce contractures and improve mobility. Discussion: The findings support the therapeutic potential of hyaluronic acid in treating joint contractures, suggesting a beneficial approach for post-immobilization recovery in clinical settings.

Keywords

  • hyaluronic acid
  • knee joint contractures
  • arthrogenic contractures
  • range of motion
  • rat model
  • intra-articular injection