The study aims to develop a memetic strategic intervention material (SIM) in Filipino 10 to address the least learned competency among Grade 10 learners. A descriptive-developmental design was used throughout the study. Descriptive analysis was used to obtain the least learned competency in the second quarter of the Filipino exam using the mean percentage score. The identified least learned competency resulting in an MPS of 23.8 as not mastered will be the basis for developing memetic SIM. The development phase begins with planning the proposed memetic content of the strategic intervention material (SIM) using a Microsoft PowerPoint presentation to assist the class point in enhancing the memetic SIM. The memetic SIM consists of a title card, guide card, activity card, assessment card, enrichment card, reference card, and answer key card. The instructional materials were scrutinized and evaluated by the master teachers in Filipino using the evaluation rating sheet for non-printed materials scoring based on DM No. 441, s. 2019. Three reviewers examined indicators of content quality, instructional quality, technical quality, and other findings. Based on the analysis results, the memetic SIM got a total mean of 4.0 with a very satisfactory description and passed the quality assurance, further improvements in content and technical aspects were suggested. The SIM was recommended for further quality assurance for wide dissemination provided that all the suggestions were made accordingly.