Background: Listening to Quran is a sort of prayers which is considered, according to the Islam heritage, as remedy for ailments which are potentially related to stress. It is well accepted that hypertension is partly related to stress, therefore, the current study aim at testing the possible effect of listening to Quran on blood pressure among hypertensive patients.  

Subjects and Methods: Through a pre post intervention study, 103 hypertensive patients were selected randomly from attendants of the chronic disease clinic in Qwaiza center, where their blood pressure and heart rate were measured at baseline, after five minutes, and after listening to Quran for 10 minutes. Main outcome was the difference between the second and third readings, that was tested by paired sample t test at a level of significance <0.05.

Main Results: There was significant reduction in blood pressure after listening to Quran, the systolic blood pressure was reduced from 135.1±13.41 at baseline down to 129.4±13.08, and diastolic blood pressure declined from 77.2±9.97 73.6±9.84. Also, the heart rate dropped significantly from 81.0/minute at baseline to 76.0/minute p<0.05.  The differences were significant among all participants regardless of their age, smoking status, BMI categories, duration of hypertension, comorbidities or the number of medications p<0.05.

Conclusion and recommendations: Listening to Quran is effective in imminent lowering of blood pressure and heart rate of hypertensive patients, further controlled trials are recommended to prove its effect and to ensure its benefits on the long term.