The main aim of the study was to create a best-fit model for predicting the level of organizational agility among personnel in ISO certified academic institutions in the Davao Region. This study adopted a non-experimental, quantitative research approach and applied a Structural Equation Model. A standardized questionnaire was used to conduct a survey among 419 teaching and non-teaching employees of an ISO accredited institution in the Davao Region. The individuals were chosen using a method called stratified random sampling. The data analysis involved using statistical approaches such as calculating the mean, determining the Pearson product-moment correlation, and applying a structural equation model. The results revealed that the level of transformational agility, readiness for change, and customer value orientation were all very high. There is a significant correlation between all external variables and the internal variable of organizational agility. The most appropriate model, Structural Model 3, was selected to demonstrate the direct and significant relationships between transformational leadership (communicating a vision and providing a suitable example), readiness to change (intentional readiness and emotional readiness), customer value orientation (reputation and quality), and organizational agility (sensing agility, decision-making agility, and action agility) among employees in Higher Education Institutions (HEIs) in the Davao Region.