Soil salinity is one of the major imperative environmental factors affecting crop yield in arid and semiarid irrigated areas. This study was conducted in order to evaluate the effect of salinity stress on yield of vegetable cowpea by using Completely Randomized Design (CRD) with four treatments and four replicates. In addition, some soil chemical properties were investigated. Seeds of vegetable cowpea variety Sene were exposed to non-saline (T1), 0.5% saline (T2), 1% saline (T3) and 1.5% saline (T4) treatments in shade house conditions. Results indicated that increasing salinity levels significantly decreased the yield of cowpea and ions concentration in the soil after harvesting. Highest pod yield (2.28 g) were observed in 0% NaCl (control), where no yield was recorded in treatment T4 (1.5% soil salinity).