Tuberculosis is still a public health problem in the world, including Indonesia. One of the focuses of interventions for controlling tuberculosis in high-risk populations is Islamic boarding schools. The purpose of this community service activity is to help people in Islamic boarding schools avoid TB transmission through an educational and participatory approach according to local potential and socio-cultural needs. The activities carried out were screening, environmental health assessment and education. The results of the screening activity showed that they had close contact with TB patients, had TB symptoms, and had TB risk factors, while the results of the environmental assessment showed that there were still many components in classrooms, bedrooms, mosques, and schools that did not meet health requirements. The results of the educational activity were that there was an increase in junior high school students knowledge about tuberculosis with an average pre-test score of 52.97 and an average post-test score of 63.75. Participants were enthusiastic in participating in this activity with an attendance percentage of 88.89%. This activity has contributed to increasing junior high school students knowledge about tuberculosis. Commitment and support from the entire community in the Islamic boarding school environment is needed in carrying out promotive and preventive activities, including routinely assessing environmental health conditions and independent TB screening.