This study assessed the career readiness of graduating students of Tourism Bachelor of Science in Tourism Management in Laguna University in relation to their perceived acceptance and intended use of industry-specific business tools, namely Amadeus, Sabre, and VIA. Grounded in the Technology Acceptance Model (TAM), it examined the relationships among perceived usefulness, perceived ease of use, behavioral intention, and perceived career readiness. A quantitative, descriptive-correlational research design was employed involving 41 graduates Tourism Management students selected through stratified purposive sampling during the academic year 2024–2025. Data were collected using a validated 26-item survey questionnaire consisting of five parts covering demographic characteristics, TAM constructs, and indicators of career readiness. A four-point Likert scale was used. Statistical treatments included frequency and percentage distribution, weighted mean, standard deviation, and the Pearson product-moment correlation coefficient (r). Findings indicated high levels of perceived usefulness, perceived ease of use, and behavioral intention to use industry-specific business tools. Respondents also demonstrated a high level of perceived career readiness. Results further revealed a significant positive relationship between students’ perceptions of industry-specific business tools and their career readiness, suggesting that favorable technology acceptance contributes to greater professional preparedness. The study concludes that integrating hands-on training in industry-specific business tools within the tourism curriculum is essential in enhancing students’ career readiness. The findings provide implications for curriculum development, institutional policy, and academic–industry collaboration aimed at producing digitally competent and job-ready tourism graduates.