Low schooling persistence among Indigenous students is disconcerting. I explored the  persistence of Indigenous students in studying college program. Qualitative research design, purposive sampling, interviews and, thematic analysis were the methods I used. The perceptions of the 12 Indigenous students revealed that Indigenous college learners face academic, social, and financial barriers, yet remain resilient and persistent through coping strategies, cultural identity, and family support. Based on these findings, higher education leaders may implement academic, financial, and culturally responsive support programs to improve Indigenous learners’ comprehension, reduce economic burdens, strengthen belonging, and promote persistence in college. Future studies may use qualitative methods to deepen understanding of Indigenous cultures and lived experiences, or quantitative methods such as multiple linear regression to examine how academic and social perceptions predict student persistence.