Climate change is a global phenomenon with consequential health effects on humans especially the children. The relationship between climatic parameters and climate related diseases in children was examined in Abuja Municipal Area Council (AMAC), Nigeria. For the purpose of this study, ten-year data on climatic parameters were obtained from Nigeria Meteorological Agency (NIMET). Hospital records of children under 13 years of age who were diagnosed with climatic related diseases were also collected. Questionnaire was designed to collect information on respondents’ socioeconomic characteristics and level of awareness of climate change. Both descriptive and inferential statistics were used in analysing the data collected. Findings revealed that as the pattern of temperature and rainfall increased, the incidences of malaria, respiratory diseases, and typhoid, pneumonia, meningitis and skin diseases decreased. The incidences of diarrhoea and measles however decreased with increase in pattern of temperature and rainfall. Efforts required in mitigating the effects of climate change on children were suggested to be policy formulation and interventions on the part of the relevant government agencies.