Many female lectures are affected in balancing their work-family life with career progression due to their multiple roles. Organizations were inability to support adequately to female lecturers for balance the multiple roles and poses that make several problems for both employers and employees. This research investigated impact of work and family life balance toward the career progression of female lectures in state universities in Sri Lanka. This is a quantitative research and data collected through questionnaire survey of 150 female lecturers in state universities in Sri Lanka. Purposive sampling technique used to collect data and linear regression, correlation and descriptive statistics were used to analyze data with the tool of SPSS. According to the collected data, family members support play a vital positive role to balance their work life and family life with the career progression. Study revealed that there is an unbalance between work-family life and career progression of female lectures and career progression of female lectures. Researcher recommend to make conscious effort for implement policies for leave and flexible work arrangements for female lecturers.