Background: contact dermatitis can manifest as irritant contact dermatitis and allergic contact dermatitis, which can occur in acute or chronic forms. Content: dermatitis of the hands is a chronic disease with significant long-term negative impacts on quality of life and an economic burden on society. Hand dermatitis is defined as eczema or dermatitis located on the hand and / or wrist. Clinical manifestations include macules, papules, vesicles, and edema in the acute stage, and in the chronic stage, crusts, scales, hyperkeratosis, and fissures are the predominant symptoms. The subjective symptoms include itching, burning, pain, sleep disturbances and mood disorders Conclusion: Washing your hands too often can cause various changes in skin texture, from progression to xerosis cutis to irritant contact dermatitis or, although rarely, allergic contact dermatitis can still occur.