In the midst of the evolution of the healthcare landscape, the intricate relationship between spiritual well-being and overall health has become a focal point of research, prompting the conduct of a literature review to unveil the profound impact of spirituality on individual individual health aspects such as mental health, physical health, Quality of Life (QoL). In this research, a literature review approach is utilized. The data collection process consists of obtaining articles from three databases: Web of Science, PubMed, and Google Scholar. The search involves the use of keywords such as “Spirituality,” “Religiousity,” and Health,. Numerous studies have discussed the role of spirituality and religiosity in various health aspects such as mental health, health status, and Quality of Life. Many of these studies have found a positive correlation between high levels of spirituality and lower rates of depression, anxiety, and stress. Spirituality and religiosity guide individuals to utilize them as positive coping mechanisms. Some studies have also identified associations between spirituality, religiosity, and individual health behaviors. Those with strong spirituality and religiosity tend to exhibit better health behaviors, such as lower alcohol consumption.