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Case Report: Fraser Syndrome. A Stepwise Management Approach in a Very Rare Condition

Open Access
Journal Type:Case Report
Subject Field:Surgery
Downloads:14
Publish Date:January 29, 2026 5:20 am
Views:81
Volume:189, Issue: 1, January, 2026
Subject:Medicine, Health & Food
Pages:202-210

Abstract

Fraser syndrome is a rare genetic disorder inherited in an autosomal recessive manner. This disorder's prevalence is

estimated at around 0.20 per 100,000 births in Europe, according to the European Surveillance of Congenital Anomalies

(EUROCAT). Here, we reported a bilateral cryptophthalmos case in a four-month-old infant with complete unilateral cleft

lip and palate and other syndromic features. We have planned a meticulously staged operation. The first step is

cheilonasoraphy, which treats nasal deformity. The hope is to improve the patient's nutritional intake to support the next

stage of the operation. Fraser syndrome is a rare medical condition that can make diagnosing and collecting data on missed

cases difficult. It's important to consider other diagnostic criteria carefully to avoid confusing the condition with other

congenital malformations.

Staged management is a viable option for improving a patient's physiological condition to aid the healing process and

support the next stage of the operation.

© 2026 International Journal of Research Publications (IJRP). All rights reserved.